Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333967 | 0.90 | RARB (0.50) | NPC1RAB9ANR5A1RXRARXRB | |
| SCHEMBL29118770 | 0.89 | NR5A1 (0.42) | NPC1RAB9ANR5A1MAPT | |
| SCHEMBL9547776 | 0.88 | MEN1 (0.48) | RAB9ASMN1; SMN2MAOBNR5A1 | |
| SCHEMBL9547848 | 0.85 | FFAR1 (0.46) | APPFFAR1POLBMAOBNR5A1 | |
| SCHEMBL9547770 | 0.85 | PLA2G10 (0.49) | FFAR1RAB9ASMN1; SMN2 | |
| SCHEMBL9126836 | 0.78 | ALOX5 (0.50) | RAB9ASMN1; SMN2 | |
| SCHEMBL9547791 | 0.76 | ALOX5 (0.49) | RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL9547785 | 0.75 | NR5A1 (0.56) | SMN1; SMN2NR5A1ALDH1A1 | |
| SCHEMBL9761610 | 0.75 | NR5A1 (0.56) | SMN1; SMN2NR5A1ALDH1A1 | |
| SCHEMBL9547755 | 0.75 | NR5A1 (0.56) | SMN1; SMN2NR5A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0288297-A2 | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-26 | — | — | EP | disclosed |