Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547770 | 0.96 | PLA2G10 (0.49) | MEN1RAB9AKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL9126836 | 0.89 | ALOX5 (0.50) | MEN1RAB9AKMT2ASMN1; SMN2PLA2G10 | |
| SCHEMBL9547791 | 0.89 | ALOX5 (0.49) | MEN1RAB9AKMT2ASMN1; SMN2ALOX5 | |
| SCHEMBL9547852 | 0.88 | APP (0.48) | RAB9ASMN1; SMN2NR5A1MAOB | |
| SCHEMBL10333967 | 0.88 | RARB (0.50) | RAB9ALTA4HNR5A1 | |
| SCHEMBL9547745 | 0.85 | ACACB (0.51) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4034303 | 0.85 | ALOX5 (0.49) | MEN1RAB9AKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL15923575 | 0.84 | LTA4H (0.66) | MEN1RAB9AKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL27974031 | 0.84 | LTA4H (0.66) | MEN1RAB9AKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL10770568 | 0.84 | CTRC (0.51) | MEN1RAB9AKMT2ASMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |