Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9548023 | 0.86 | PTGS2 (0.65) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| Fr-122047 SCHEMBL9548128 | 0.84 | PTGS2 (1.00) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL9548056 | 0.84 | ALDH1A1 (0.82) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| Fr-122047 SCHEMBL9548002 | 0.83 | PTGS2 (0.98) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| Fr-122047 SCHEMBL15531779 | 0.82 | PTGS2 (0.95) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL9548039 | 0.82 | PTGS2 (0.78) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL9548091 | 0.81 | ALDH1A1 (0.77) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL9548105 | 0.81 | PTGS2 (0.77) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL9548082 | 0.80 | PTGS2 (0.79) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL9547994 | 0.80 | PTGS2 (0.75) | PTGS2ALDH1A1CYP3A4KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |