Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.82 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 2/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.82 |
| ▸ | GLA | P06280 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fr-122047 SCHEMBL9548128 | 0.90 | PTGS2 (1.00) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| Fr-122047 SCHEMBL9548002 | 0.89 | PTGS2 (0.98) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| Fr-122047 SCHEMBL15531779 | 0.88 | PTGS2 (0.95) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| SCHEMBL9548039 | 0.88 | PTGS2 (0.78) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| SCHEMBL9548105 | 0.87 | PTGS2 (0.77) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| SCHEMBL9548091 | 0.87 | ALDH1A1 (0.77) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| SCHEMBL9548082 | 0.86 | PTGS2 (0.79) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9547994 | 0.86 | PTGS2 (0.75) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9547997 | 0.84 | PTGS2 (0.76) | ALDH1A1PTGS2KDM4EKMT2AMEN1 | |
| SCHEMBL9548040 | 0.84 | PTGS2 (0.72) | ALDH1A1PTGS2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |