Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648836 | 0.88 | ADRB2 (0.66) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL9548053 | 0.87 | SLC6A4 (0.60) | ADRB2ADRA1AADRB1CYP2D6HTR1A | |
| Acetic Acid SCHEMBL10652049 | 0.84 | ADRB2 (0.67) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11470324 | 0.81 | ADRB2 (0.59) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL8985958 | 0.80 | ADRB1 (0.80) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11480657 | 0.78 | ADRB2 (0.68) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11480654 | 0.78 | ADRB2 (0.68) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11480322 | 0.78 | ADRA1A (0.63) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11470328 | 0.77 | ADRB2 (0.60) | ADRB2ADRA1AADRB1ADRA1DADRA1B | |
| SCHEMBL11020328 | 0.77 | ADRB2 (0.63) | ADRB2ADRA1AADRB1ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198587-A | Adrenergic Blocking Agents, Hypotensive Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5063246-A | Hypotensive | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| US-4880841-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |