Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548079 | 0.87 | ADRB2 (0.57) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL9548061 | 0.81 | SLC6A4 (0.58) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL4684534 | 0.81 | ADRA1A (0.71) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL8855337 | 0.79 | ADRB2 (0.82) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL10648836 | 0.76 | ADRB2 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL3723459 | 0.75 | ADRB1 (0.77) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| SCHEMBL11817096 | 0.75 | ADRB2 (0.83) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL29387627 | 0.75 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL78008 | 0.75 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL6510272 | 0.75 | SLC6A4 (0.66) | SLC6A4ADRA1AHTR1ASLC6A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57028040-A | — | — | None | — | — | JP | disclosed |
| US-5198587-A | Adrenergic Blocking Agents, Hypotensive Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-5063246-A | Hypotensive | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| US-4880841-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| JP-S5728040-A | PHENYLETHANOLAMINE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1982-02-15 | — | — | JP | disclosed |