SCHEMBL9548212

SCHEMBL9548212

CC(OS(=O)(=O)O)S(=O)(=O)c1ccc(N)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CYP3A4 P08684 4/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 2/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5047408 0.82 CTDSP1 (0.39) CA1CA2CA9CA12CA4
SCHEMBL1819324 0.78 TSHR (0.48) CA1CA2CA9CA12CA4
SCHEMBL9548233 0.77 ALDH1A1 (0.40) CYP3A4ALDH1A1HSD17B10THRBHPGD
SCHEMBL8472933 0.76 CASP6 (0.43) ALDH1A1HSD17B10KDM4EMEN1GAA
SCHEMBL8953417 0.76 ALDH1A1 (0.54) CA1CA2CA9CA12CA4
SCHEMBL879153 0.73 CA1 (0.68) CA1CA2CA9CA12CA4
SCHEMBL31208448 0.73 CA1 (0.68) CA1CA2CA9CA12CA4
SCHEMBL20526669 0.73 CA1 (0.61) CA1CA2CA9CA12CA4
SCHEMBL13744645 0.72 SNCA (0.43) ALDH1A1TSHRHSD17B10HPGDMEN1
SCHEMBL13196224 0.72 LMNA (0.38) ALDH1A1TSHRHPGDRECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed