Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670337 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL5047408 | 0.77 | CTDSP1 (0.39) | ALDH1A1TDP1KDM4EHSD17B10KMT2A | |
| SCHEMBL9548212 | 0.77 | CA1 (0.50) | ALDH1A1CYP3A4ALOX15KDM4EHSD17B10 | |
| SCHEMBL1819324 | 0.76 | TSHR (0.48) | ALDH1A1TDP1CYP3A4LMNAKMT2A | |
| SCHEMBL1018611 | 0.75 | LMNA (0.61) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL344111 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL8953417 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4HSD17B10LMNA | |
| SCHEMBL712851 | 0.73 | MAPT (0.57) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL9796022 | 0.72 | ADAMTS4 (0.49) | ALDH1A1TDP1CYP3A4ALOX15KDM4E | |
| SCHEMBL7098293 | 0.72 | SMN1; SMN2 (0.45) | ALDH1A1TDP1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231172-A | Water solubility | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |