Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548655 | 1.00 | HINT1 (0.40) | HINT1POLBADORA3HPRT1GSK3A | |
| SCHEMBL9548803 | 0.89 | ALDH1A1 (0.41) | ADORA3HPRT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL9548704 | 0.87 | HINT1 (0.37) | HINT1PNP | |
| SCHEMBL9548665 | 0.85 | HSP90B1 (0.38) | — | |
| SCHEMBL9548672 | 0.85 | HSP90B1 (0.38) | — | |
| SCHEMBL9548741 | 0.81 | ADORA3 (0.47) | HINT1POLBADORA3HPRT1PNP | |
| SCHEMBL9548601 | 0.81 | ADORA3 (0.47) | HINT1POLBADORA3HPRT1PNP | |
| SCHEMBL9548756 | 0.81 | ADORA3 (0.47) | HINT1POLBADORA3HPRT1PNP | |
| SCHEMBL9548596 | 0.81 | ADORA3 (0.47) | HINT1POLBADORA3HPRT1PNP | |
| SCHEMBL9548873 | 0.79 | TOP2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |