Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.42 |
| ▸ | HINT1 | P49773 | 2/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23621823 | 0.85 | PNP (0.44) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL9548809 | 0.80 | TYMP (0.51) | LMNA | |
| SCHEMBL25818680 | 0.77 | POLB (0.49) | TP53PDE4DPDE3ASMN1; SMN2AHCY | |
| SCHEMBL9548885 | 0.76 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL26782125 | 0.74 | PNP (0.51) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL15280844 | 0.73 | POLB (0.47) | TP53SMN1; SMN2AHCYP2RY1POLB | |
| SCHEMBL19887008 | 0.73 | POLB (0.47) | TP53SMN1; SMN2AHCYP2RY1POLB | |
| SCHEMBL8970868 | 0.73 | LMNA (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL22300667 | 0.73 | LMNA (0.58) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL21958777 | 0.73 | P2RY1 (0.40) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |