SCHEMBL9549578

SCHEMBL9549578

C=CC(=O)N(CCO)C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PDE4A P27815 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TOP1 P11387 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9144979 1.00 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9549571 0.87 ZDHHC20 (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9146704 0.84 ZDHHC20 (0.44) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9243605 0.84 ZDHHC20 (0.44) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9147045 0.83 TOP1 (0.37) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL806321 0.82 ZDHHC20 (0.52) LMNATOP1
SCHEMBL9143341 0.82 ZDHHC20 (0.52) LMNATOP1
SCHEMBL9144568 0.82 ZDHHC20 (0.52) LMNATOP1
SCHEMBL4774391 0.76 TOP1 (0.42) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9465084 0.76 TOP1 (0.42) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185466-A Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis KOZULIC BRANKO (CH) 1993-02-09 US claimed
US-5185466-A Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis KOZULIC BRANKO (CH) 1993-02-09 US disclosed