SCHEMBL9549817

SCHEMBL9549817

Nc1ccc(OC2(F)C(F)(F)C(F)(F)C2(F)Oc2ccc(N)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
TDP1 Q9NUW8 6/20 0.46
CYP3A4 P08684 3/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.42
MAOA P21397 2/20 0.39
MAPT P10636 5/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAOB P27338 3/20 0.38
TEAD4 Q15561 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.37
MITF O75030 1/20 0.37
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
NLRP1 Q9C000 1/20 0.37
NOD2 Q9HC29 1/20 0.37
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31738490 0.91 ALDH1A1 (0.46) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL29083172 0.79 TDP1 (0.44) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL12833362 0.78 NFE2L2 (0.37) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL9169598 0.76 CA1 (0.52) ALDH1A1TDP1CYP3A4MAPK1MAOA
SCHEMBL9167809 0.76 ESR2 (0.46) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL12833379 0.73 TDP1 (0.38) ALDH1A1TDP1CYP3A4TSHRMAPK1
SCHEMBL23154864 0.71 MAPT (0.44) ALDH1A1TDP1TSHRMAPK1MAPT
SCHEMBL9314140 0.71 CA12 (0.36)
SCHEMBL18337792 0.70 CA1 (0.50) ALDH1A1TDP1TSHRKMT2ANR4A1
SCHEMBL9171497 0.69 ALDH1A1 (0.37) ALDH1A1MAPTKMT2AGFERHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669336-B Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2022-06-17 CN claimed
CN-110669336-A Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2020-01-10 CN claimed
CN-119463143-A Polynaphthalate resin and preparation method thereof 四川大学 2025-02-18 CN disclosed
CN-111876085-B Composite bonding sheet, flexible metal laminated board and preparation method thereof 东莞东阳光科研发有限公司 2022-09-27 CN disclosed
CN-110669336-B Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2022-06-17 CN disclosed
CN-110669336-A Modified fluorine-containing polyimide resin composition and preparation method thereof 中山市鸿盛新材料有限公司 2020-01-10 CN disclosed
US-5210265-A Multistage reaction to form monomers for polymers such as polyesters by dimerization of trifluorovinyl compounds by dehalogenation and cyclization THE DOW CHEMICAL COMPANY (US) 1993-05-11 US disclosed
EP-0429618-A1 REACTIVE COMPOUNDS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1991-06-05 EP disclosed
US-5021602-A Monomers for condensation polymers THE DOW CHEMICAL COMPANY (US) 1991-06-04 US disclosed
WO-1990015044-A2 REACTIVE COMPOUNDS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed