SCHEMBL29083172

SCHEMBL29083172

Nc1ccc(OC2(Oc3ccc(N)cc3)C(F)(F)C(F)(F)C2(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.44
ALDH1A1 P00352 6/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.41
MAOA P21397 2/20 0.38
MAPT P10636 6/20 0.37
MAOB P27338 3/20 0.37
TEAD4 Q15561 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
POLB P06746 1/20 0.35
MITF O75030 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
NLRP1 Q9C000 1/20 0.35
NOD2 Q9HC29 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9549817 0.79 ALDH1A1 (0.46) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL31738490 0.79 ALDH1A1 (0.46) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL12833379 0.71 TDP1 (0.38) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL9764749 0.70 ALDH1A1 (0.36) ALDH1A1MAPTKMT2ARAB9AHPGD
SCHEMBL9751693 0.70 LMNA (0.52) ALDH1A1CYP3A4MAPK1MAPTMEN1
Benzidine SCHEMBL4057318 0.69 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL9391068 0.68 TDP1 (0.38) TDP1ALDH1A1MAPTMEN1KMT2A
SCHEMBL25283157 0.67 MAPT (0.50) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL9497883 0.67 ALDH1A1 (0.54) TDP1ALDH1A1CYP3A4TSHRMAPK1
SCHEMBL8905023 0.65 ALDH1A1 (0.46) TDP1ALDH1A1CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294855-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS Solvay Specialty Polymers Italy S.p.A. (IT) 2023-12-27 EP disclosed
CN-116848177-A Polyimide with low dielectric loss 索尔维特殊聚合物意大利有限公司 2023-10-03 CN disclosed
WO-2022175169-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-08-25 WO disclosed
WO-2022175168-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-08-25 WO disclosed