Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550432 | 0.78 | S100A4 (0.47) | S100A4APPNPC1TGM2CES1 | |
| SCHEMBL9550328 | 0.78 | APP (0.46) | APPNPC1CA1CA2CA4 | |
| SCHEMBL9550347 | 0.78 | AR (0.43) | ESR1ESR2DDB1CRBNCA1 | |
| SCHEMBL9550323 | 0.76 | CA12 (0.43) | POLBCA9ALDH1A1MEN1KMT2A | |
| SCHEMBL9143697 | 0.76 | CA12 (0.43) | POLBCA9ALDH1A1MEN1KMT2A | |
| SCHEMBL6651899 | 0.75 | ESR1 (0.59) | ESR1ESR2S100A4APPPOLB | |
| SCHEMBL1783796 | 0.75 | APP (0.66) | ESR1ESR2S100A4APPPOLB | |
| SCHEMBL9550352 | 0.73 | PTPRC (0.53) | S100A4PTPRCCA1CA2CA7 | |
| SCHEMBL9550303 | 0.73 | ESR1 (0.33) | ESR1ESR2APPCA1CA2 | |
| SCHEMBL19200191 | 0.71 | ESR1 (0.50) | ESR1ESR2S100A4APPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |