Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | USP8 | P40818 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 2/20 | 0.42 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550316 | 0.78 | ESR1 (0.51) | S100A4NPC1APPMEN1KMT2A | |
| SCHEMBL1704408 | 0.78 | S100A4 (0.52) | S100A4PPOXNPC1HSP90AA1MEN1 | |
| SCHEMBL9550328 | 0.77 | APP (0.46) | USP8USP7NPC1APP | |
| SCHEMBL9550347 | 0.77 | AR (0.43) | USP8USP7USP47GRM1GRM4 | |
| SCHEMBL28618112 | 0.75 | S100A4 (0.54) | S100A4PPOXNPC1HSP90AA1MEN1 | |
| SCHEMBL9550323 | 0.74 | CA12 (0.43) | MEN1KMT2A | |
| SCHEMBL9143697 | 0.74 | CA12 (0.43) | MEN1KMT2A | |
| SCHEMBL2239437 | 0.74 | S100A4 (0.52) | S100A4PPOXNPC1HSP90AA1MEN1 | |
| SCHEMBL9126362 | 0.74 | S100A4 (0.52) | S100A4PPOXNPC1GRM1GRM4 | |
| SCHEMBL1500415 | 0.74 | ALDH1A1 (0.55) | S100A4PPOXAPPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |