Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | USP8 | P40818 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550316 | 0.78 | ESR1 (0.51) | DDB1CRBNCA1CA2CA7 | |
| SCHEMBL9550328 | 0.77 | APP (0.46) | USP8USP7CA1CA2CA7 | |
| SCHEMBL9550432 | 0.77 | S100A4 (0.47) | USP8USP7USP47GRM1GRM4 | |
| SCHEMBL9550303 | 0.75 | ESR1 (0.33) | CA1CA2CA9ESR1ESR2 | |
| SCHEMBL9143697 | 0.74 | CA12 (0.43) | CA9 | |
| SCHEMBL9550323 | 0.74 | CA12 (0.43) | CA9 | |
| SCHEMBL8417452 | 0.74 | ALDH1A1 (0.55) | ARDDB1CRBNCA1CA2 | |
| SCHEMBL22166573 | 0.73 | AR (0.43) | ARUSP8USP7USP47DDB1 | |
| SCHEMBL1734116 | 0.72 | ESR1 (0.58) | ARCA1CA2CA9GRM1 | |
| SCHEMBL9550352 | 0.72 | PTPRC (0.53) | CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0484381-A1 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |