Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | FEN1 | P39748 | 1/20 | 0.64 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TYMS | P04818 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | TAF1 | P21675 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213400 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL11768082 | 0.78 | KDM4E (0.70) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL9127705 | 0.78 | KDM4E (0.70) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL7712153 | 0.78 | MAPT (1.00) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL10267893 | 0.77 | ALDH1A1 (0.77) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL11712317 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL9550468 | 0.75 | ERCC1 (0.57) | ALDH1A1KDM4EMAPTCYP1A2ERCC1 | |
| SCHEMBL7735555 | 0.75 | KDM4E (0.68) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL3437810 | 0.75 | TYMS (0.71) | ALDH1A1KDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL17954591 | 0.75 | KDM4E (0.52) | ALDH1A1KDM4EPOLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |