SCHEMBL9550468

SCHEMBL9550468

N#CN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.57
FEN1 P39748 1/20 0.57
ERCC4 Q92889 1/20 0.57
HEXA P06865 4/20 0.53
HEXB P07686 4/20 0.53
ALDH1A1 P00352 8/20 0.52
KDM4E B2RXH2 5/20 0.52
HPGD P15428 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
HSD17B10 Q99714 3/20 0.52
CYP1B1 Q16678 1/20 0.52
CES2 O00748 1/20 0.50
BCHE P06276 1/20 0.50
CES1 P23141 1/20 0.50
MCL1 Q07820 1/20 0.50
NPSR1 Q6W5P4 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550323 0.81 CA12 (0.43) ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL9143697 0.81 CA12 (0.43) ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL9550381 0.79 NTRK1 (0.61) KDM4EMEN1KMT2AMCL1CYP1A2
SCHEMBL6734026 0.77 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL28891794 0.76 ERCC1 (0.52) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL9550336 0.75 ALDH1A1 (0.64) ERCC1FEN1ERCC4ALDH1A1KDM4E
SCHEMBL27752410 0.74 ERCC1 (0.65) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL24453236 0.72 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL21099252 0.72 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL4604913 0.72 MPO (0.70) ERCC1FEN1ERCC4HEXAHEXB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0484381-A1 N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF HENKEL RESEARCH CORPORATION (US) 1992-05-13 EP claimed
WO-1991001307-A2 N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF HENKEL RESEARCH CORPORATION (US) 1991-02-07 WO claimed
CN-117777751-A Cyanine dye and application thereof 中国科学技术大学 2024-03-29 CN disclosed
CN-107847188-B Composition for latent fingerprint detection 东亚合成株式会社 2022-03-25 CN disclosed
EP-3329846-B1 COMPOSITION FOR DETECTING LATENT FINGERPRINT TOAGOSEI CO LTD (JP) 2021-07-14 EP disclosed
US-20180368740-A1 COMPOSITION FOR DETECTING LATENT FINGERPRINT TOAGOSEI CO., LTD (JP) 2018-12-27 US disclosed
EP-3329846-A1 COMPOSITION FOR DETECTING LATENT FINGERPRINT Toagosei Co., Ltd. (JP) 2018-06-06 EP disclosed
US-5216173-A Curing agents for epoxy resins; polyimides HENKEL RESEARCH CORPORATION (US) 1993-06-01 US disclosed