Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550355 | 0.89 | FOLH1 (0.55) | RXRARXRBMRGPRX4MEN1NPC1 | |
| SCHEMBL9550479 | 0.88 | NPC1 (0.47) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL3814086 | 0.82 | PTGER1 (0.64) | RXRARXRBRXRGMRGPRX4NR4A2 | |
| SCHEMBL1388211 | 0.80 | PTGER1 (0.60) | RXRARXRBRXRGMRGPRX4NR4A2 | |
| SCHEMBL1648397 | 0.79 | LRRK2 (0.67) | RXRARXRBRXRGMRGPRX4NR4A2 | |
| SCHEMBL19554264 | 0.79 | MRGPRX4 (0.53) | RXRARXRBMRGPRX4MEN1NPC1 | |
| SCHEMBL20535332 | 0.78 | MRGPRX4 (0.57) | MRGPRX4MAOB | |
| SCHEMBL9623127 | 0.78 | MRGPRX4 (0.43) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL2902027 | 0.77 | RXRA (0.68) | RXRARXRBRXRGMRGPRX4NR4A2 | |
| SCHEMBL5839670 | 0.77 | FABP3 (0.68) | RXRARXRBRXRGMRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236931-A | Treating anxiety, psychosis, cognitive dysfunction, migrane, cluster headache, trigeminal neuralgia emesis and impaired gastric motility | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-08-17 | — | — | US | disclosed |