SCHEMBL9550628

SCHEMBL9550628

C=C(C)COc1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 14/20 0.54
▸ FAAH O00519 5/20 0.48
▸ HSP90AA1 P07900 3/20 0.46
▸ PKM P14618 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ HTT P42858 2/20 0.46
▸ LMNA P02545 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ CCR6 P51684 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ NPSR1 Q6W5P4 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ GPR174 Q9BXC1 1/20 0.46
▸ CACNA1B Q00975 1/20 0.45
▸ APBA1 Q02410 1/20 0.45
▸ DDAH1 O94760 1/20 0.42
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550629 0.83 MGLL (0.58) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL31050182 0.80 KMT2A (0.64) ALDH1A1MEN1KMT2AGPR174POLB
SCHEMBL10338925 0.78 GPR174 (0.58) PKMALDH1A1LMNAMEN1KMT2A
SCHEMBL3676454 0.78 LMNA (0.66) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL21515067 0.78 MGLL (0.58) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL8542401 0.77 MGLL (0.62) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL8526538 0.77 MGLL (0.62) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL27733199 0.76 MGLL (0.49) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL3668333 0.75 MGLL (0.60) MGLLFAAHHSP90AA1PKMALDH1A1
SCHEMBL26083585 0.75 MGLL (0.64) MGLLHSP90AA1ALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208634-B1 MALEIMIDES AND THERMOHARDENING COMPOSITIONS CONTAINING THEM RHONE-POULENC CHIMIE (FR) 1989-09-06 — — EP claimed
US-4788295-A Functional monomaleimide and thermosetting composition therefrom RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-11-29 — — US claimed
US-5206338-A Molding materials; nontoxic; films; foams; fillers; lamination for aerospace and electrical products CIBA-GEIGY CORPORATION (US) 1993-04-27 — — US disclosed
US-5122589-A Prepregs; filament wound shapes RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US disclosed
US-5122590-A Addition-condensation copolymer comprising an N,N*-bismaleimide, hindered aromatic diprimary diamine, a diamino-s-triazine, a halogenated epoxy resin and a diallyl oxylated benzene; heat resistance; prepregs RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US disclosed
US-5053474-A NOVEL IMIDO POLYMERS RHONE-POULENC CHIMIE (FR) 1991-10-01 — — US disclosed
US-5034503-A Novel imido copolymers RHONE-POULENC CHIMIE (FR) 1991-07-23 — — US disclosed
US-4886868-A MOLDING MATERIALS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-12-12 — — US disclosed
US-4883883-A IMPROVED MECHANICAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-11-28 — — US disclosed
US-4847343-A DIAMINE CONTAINING POLYSILOXANE MALEIMDIES RHONE-POULENC CHIMIE (FR) 1989-07-11 — — US disclosed
US-4847344-A POLYSILOXANE COPOLYMERS, LAMINATION RHONE-POULENC CHIMIE (FR) 1989-07-11 — — US disclosed
US-4839440-A IMPROVED THERMAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-06-13 — — US disclosed
US-4829138-A MOLDING MATERIALS RHONE-POULENC CHIMIE (FR) 1989-05-09 — — US disclosed
US-4788295-A Functional monomaleimide and thermosetting composition therefrom RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-11-29 — — US disclosed
US-4777237-A HEAT-RESISTANT THERMOSETTING MOLDING MATERIALS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1988-10-11 — — US disclosed
US-4742141-A HEAT-STABLE; IMPREGNANTS; COATING OR MOLDING RESINS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-03 — — US disclosed
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