SCHEMBL9550629

SCHEMBL9550629

C=C(C)COc1cccc(N2C(=O)C=CC2=O)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 11/20 0.58
▸ FAAH O00519 4/20 0.51
▸ HSP90AA1 P07900 3/20 0.49
▸ HPN P05981 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ PKM P14618 2/20 0.44
▸ HTT P42858 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MAPT P10636 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ GRM5 P41594 1/20 0.40
▸ GPR174 Q9BXC1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9550628 0.83 MGLL (0.54) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL29065797 0.79 MGLL (0.66) MGLLFAAHHSP90AA1HPNALDH1A1
SCHEMBL9622079 0.79 LMNA (0.52) HSP90AA1ALDH1A1PKMHTTMEN1
SCHEMBL11614328 0.77 MGLL (0.58) MGLLFAAHHSP90AA1HPNALDH1A1
SCHEMBL9123872 0.77 MEN1 (0.37) MGLLHSP90AA1ALDH1A1PKMHTT
SCHEMBL13133152 0.77 MGLL (0.58) MGLLFAAHHSP90AA1ALDH1A1PKM
SCHEMBL9435438 0.76 MGLL (0.57) MGLLFAAHHSP90AA1HPNALDH1A1
SCHEMBL13133155 0.75 MGLL (0.65) MGLLFAAHHSP90AA1ALDH1A1HTT
SCHEMBL1092175 0.75 MAOB (0.60) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL29836551 0.75 MGLL (0.65) MGLLFAAHHSP90AA1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208634-B1 MALEIMIDES AND THERMOHARDENING COMPOSITIONS CONTAINING THEM RHONE-POULENC CHIMIE (FR) 1989-09-06 — — EP claimed
US-4788295-A Functional monomaleimide and thermosetting composition therefrom RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-11-29 — — US claimed
US-5206338-A Molding materials; nontoxic; films; foams; fillers; lamination for aerospace and electrical products CIBA-GEIGY CORPORATION (US) 1993-04-27 — — US disclosed
US-5122589-A Prepregs; filament wound shapes RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US disclosed
US-5122590-A Addition-condensation copolymer comprising an N,N*-bismaleimide, hindered aromatic diprimary diamine, a diamino-s-triazine, a halogenated epoxy resin and a diallyl oxylated benzene; heat resistance; prepregs RHONE-POULENC CHIMIE (FR) 1992-06-16 — — US disclosed
US-5053474-A NOVEL IMIDO POLYMERS RHONE-POULENC CHIMIE (FR) 1991-10-01 — — US disclosed
US-5034503-A Novel imido copolymers RHONE-POULENC CHIMIE (FR) 1991-07-23 — — US disclosed
US-4886868-A MOLDING MATERIALS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-12-12 — — US disclosed
US-4883883-A IMPROVED MECHANICAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-11-28 — — US disclosed
US-4847343-A DIAMINE CONTAINING POLYSILOXANE MALEIMDIES RHONE-POULENC CHIMIE (FR) 1989-07-11 — — US disclosed
US-4847344-A POLYSILOXANE COPOLYMERS, LAMINATION RHONE-POULENC CHIMIE (FR) 1989-07-11 — — US disclosed
US-4839440-A IMPROVED THERMAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-06-13 — — US disclosed
US-4829138-A MOLDING MATERIALS RHONE-POULENC CHIMIE (FR) 1989-05-09 — — US disclosed
US-4788295-A Functional monomaleimide and thermosetting composition therefrom RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-11-29 — — US disclosed
US-4777237-A HEAT-RESISTANT THERMOSETTING MOLDING MATERIALS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1988-10-11 — — US disclosed
US-4742141-A HEAT-STABLE; IMPREGNANTS; COATING OR MOLDING RESINS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-03 — — US disclosed
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