Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706102 | 0.75 | MAPT (0.59) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL9669287 | 0.75 | DRD2 (0.42) | CHRNA7 | |
| SCHEMBL1787546 | 0.72 | MAPT (0.62) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL3948630 | 0.67 | MAPT (0.43) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL443555 | 0.67 | MAOA (0.50) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL12043446 | 0.67 | HTR5A (0.37) | MAPTKDM4EALDH1A1GAAACHE | |
| SCHEMBL14481557 | 0.66 | MAPT (0.68) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL4571013 | 0.66 | CYP3A4 (1.00) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL22953335 | 0.66 | CYP3A4 (1.00) | MAPTCYP3A4KDM4EMAOAALDH1A1 | |
| SCHEMBL2594537 | 0.66 | MAPT (0.68) | MAPTCYP3A4KDM4EMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569380-A1 | ACRIDINE DERIVATIVES. | GLAXO LAB SA (FR) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012132-A1 | ACRIDINE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1992-07-23 | — | — | WO | disclosed |