Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | NAAA | Q02083 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556926 | 0.95 | NPC1 (0.57) | MAPTRXFP1SIGMAR1NAAANPC1 | |
| SCHEMBL9557179 | 0.90 | MAOA (0.52) | MAPTRXFP1SIGMAR1NAAANPC1 | |
| SCHEMBL9557053 | 0.88 | NAAA (0.53) | MAPTRXFP1SIGMAR1NAAANPC1 | |
| SCHEMBL9557168 | 0.84 | NPC1 (0.54) | MAPTSIGMAR1NAAANPC1TDP1 | |
| SCHEMBL9557028 | 0.83 | NAAA (0.58) | MAPTNAAAHDAC1HDAC2HDAC3 | |
| SCHEMBL7376148 | 0.82 | NPC1 (0.76) | NAAANPC1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL9557029 | 0.80 | FKBP1A (0.56) | SIGMAR1FKBP1AALOX5SMN1; SMN2 | |
| SCHEMBL1953978 | 0.80 | FKBP1A (0.80) | MAPTSIGMAR1NAAANPC1TDP1 | |
| SCHEMBL7447522 | 0.80 | NAAA (0.58) | MAPTSIGMAR1NAAANPC1TDP1 | |
| SCHEMBL9557071 | 0.80 | NPC1 (0.58) | MAPTSIGMAR1NAAANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |