Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557419 | 0.94 | CES2 (0.54) | CES2CES1HTTHPGDKDM4E | |
| SCHEMBL11212295 | 0.84 | CES2 (0.61) | CES2CES1HPGDKDM4ECA1 | |
| SCHEMBL9557523 | 0.81 | CES2 (0.54) | CES2CES1KDM4EPARP1SMN1; SMN2 | |
| SCHEMBL9557819 | 0.81 | NPC1 (0.50) | CES2CES1HTTPARP1SMN1; SMN2 | |
| SCHEMBL9557162 | 0.81 | ALDH1A1 (0.43) | CES2CES1HTTHPGDCA2 | |
| SCHEMBL9557630 | 0.80 | DRD4 (0.47) | CES2CES1KDM4EPARP1ALDH1A1 | |
| SCHEMBL9557542 | 0.80 | OPRM1 (0.47) | CES2CES1HTTHPGDKDM4E | |
| SCHEMBL9557376 | 0.79 | KMT2A (0.42) | CES2CES1CA1CA2RECQL | |
| SCHEMBL9557820 | 0.79 | TRPA1 (0.42) | CES2CES1HPGDCA1CA2 | |
| SCHEMBL9557398 | 0.79 | NR1H4 (0.48) | HTTHPGDALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |