Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557956 | 0.91 | MEN1 (0.49) | MEN1KMT2AALDH1A1ALOX15CES2 | |
| SCHEMBL9557556 | 0.81 | KMT2A (0.49) | MEN1KMT2AHTTKDM4EHPGD | |
| SCHEMBL9557317 | 0.80 | POLB (0.54) | HTTPOLBHPGD | |
| SCHEMBL9557605 | 0.80 | MEN1 (0.43) | MEN1KMT2AALDH1A1ALOX15CES2 | |
| SCHEMBL12084858 | 0.79 | CES2 (0.52) | MEN1KMT2AALDH1A1ALOX15CES2 | |
| SCHEMBL9557479 | 0.78 | NR4A1 (0.51) | MEN1KMT2AALDH1A1ALOX15HTT | |
| SCHEMBL9557258 | 0.78 | CTSD (0.49) | HTTRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9557495 | 0.77 | CES2 (0.41) | MEN1KMT2ACES2CES1POLB | |
| SCHEMBL254968 | 0.76 | MEN1 (0.61) | MEN1KMT2AALDH1A1ALOX15CES2 | |
| SCHEMBL8173976 | 0.76 | MEN1 (0.49) | MEN1KMT2AALDH1A1ALOX15CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |