Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558057 | 0.86 | TSHR (0.36) | HSP90AA1HSP90AB1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL9557549 | 0.79 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2TSHRMAPTALDH1A1 | |
| SCHEMBL9826137 | 0.76 | ALDH1A1 (0.39) | HSP90AA1HSP90AB1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL11782049 | 0.72 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1KMT2ATSHRALDH1A1 | |
| SCHEMBL9557703 | 0.71 | TSHR (0.41) | HSP90AA1HSP90AB1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9557674 | 0.67 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL11782048 | 0.65 | TSHR (0.54) | HSP90AA1HSP90AB1TSHRHPGD | |
| SCHEMBL3365999 | 0.65 | TSHR (0.52) | HSP90AA1HSP90AB1TSHRHPGD | |
| SCHEMBL9558054 | 0.65 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1GAAHPGD | |
| SCHEMBL9557591 | 0.63 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |