Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825038 | 0.77 | POLB (0.50) | ALDH1A1HPGDRAB9ALMNAPOLB | |
| SCHEMBL9558057 | 0.77 | TSHR (0.36) | ALDH1A1HPGDGAAEPHX2HTT | |
| SCHEMBL9557402 | 0.76 | HSP90AA1 (0.37) | ALDH1A1HPGDGAAEPHX2KMT2A | |
| SCHEMBL11782049 | 0.72 | HSP90AA1 (0.38) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL10721492 | 0.71 | HPGD (0.41) | ALDH1A1HPGDRAB9AGRNSORT1 | |
| SCHEMBL9825414 | 0.69 | CYP2C9 (0.48) | HPGDRAB9AHTTGRNSORT1 | |
| SCHEMBL9496095 | 0.67 | MEN1 (0.51) | HPGDRAB9AHTTGRNSORT1 | |
| SCHEMBL3365999 | 0.65 | TSHR (0.52) | HPGDGRNSORT1TSHRHSP90AA1 | |
| SCHEMBL10718172 | 0.63 | HPGD (0.42) | HPGDRAB9AGRNSORT1KMT2A | |
| SCHEMBL7263572 | 0.63 | TTR (0.68) | ALDH1A1HPGDLMNATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |