Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558176 | 0.88 | SLC6A2 (0.43) | TSHRSLC6A4SLC6A3SLC6A2HSP90AA1 | |
| SCHEMBL10721492 | 0.78 | HPGD (0.41) | TSHRSLC6A4SLC6A3SLC6A2HPGD | |
| SCHEMBL9557821 | 0.74 | HSP90AA1 (0.38) | HSP90AA1HPGDALDH1A1KDM4EGPR139 | |
| SCHEMBL11782048 | 0.72 | TSHR (0.54) | TSHRSLC6A4SLC6A3SLC6A2HSP90AA1 | |
| SCHEMBL9557549 | 0.71 | ALDH1A1 (0.46) | TSHRHPGDALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3365999 | 0.71 | TSHR (0.52) | TSHRSLC6A4SLC6A3SLC6A2HSP90AA1 | |
| SCHEMBL9557402 | 0.71 | HSP90AA1 (0.37) | TSHRHSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL11782487 | 0.69 | TSHR (0.50) | TSHRSLC6A4SLC6A3SLC6A2HSP90AA1 | |
| SCHEMBL9557502 | 0.69 | TSHR (0.45) | TSHRSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11785050 | 0.67 | TSHR (0.55) | TSHRSLC6A4SLC6A3SLC6A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |