Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557295 | 0.87 | MAPT (0.51) | CES2KMT2AMAPTALDH1A1ABCB1 | |
| SCHEMBL9557493 | 0.87 | CTSD (0.44) | KMT2AMAPTLMNAALDH1A1POLB | |
| SCHEMBL9557180 | 0.85 | CES2 (0.53) | CES2KMT2AMAPTMEN1LMNA | |
| SCHEMBL9557915 | 0.84 | CES1 (0.54) | CES2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9557751 | 0.83 | TP53 (0.52) | CES2KMT2AMAPTMEN1LMNA | |
| SCHEMBL9557366 | 0.82 | ATM (0.56) | CES2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9557760 | 0.81 | POLB (0.43) | CES2KMT2AMAPTMEN1LMNA | |
| SCHEMBL9557737 | 0.79 | ALDH1A1 (0.55) | CES2KMT2AMAPTMEN1LMNA | |
| SCHEMBL9557683 | 0.79 | CTSD (0.49) | MAPTLMNAALDH1A1CYP1A2HTT | |
| SCHEMBL9557616 | 0.78 | MAPK1 (0.50) | CES2KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |