Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557751 | 0.91 | TP53 (0.52) | ATMTP53CES2CES1ALDH1A1 | |
| SCHEMBL9557915 | 0.89 | CES1 (0.54) | ATMCES2CES1ALDH1A1RAB9A | |
| SCHEMBL9557737 | 0.86 | ALDH1A1 (0.55) | ATMTP53CES2CES1ALDH1A1 | |
| SCHEMBL9557653 | 0.84 | ALDH1A1 (0.50) | ATMTP53ALOX5CES2CES1 | |
| SCHEMBL9557616 | 0.83 | MAPK1 (0.50) | CES2CES1ALDH1A1MAPTCRHBP | |
| SCHEMBL8174989 | 0.83 | POLB (0.50) | ALDH1A1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL9557474 | 0.82 | CES2 (0.56) | ATMCES2CES1ALDH1A1ABCB1 | |
| SCHEMBL9557295 | 0.81 | MAPT (0.51) | TP53CES2ALDH1A1ABCB1RAB9A | |
| SCHEMBL9558223 | 0.79 | ABCB1 (0.48) | ABCB1HTTMEN1KMT2ACYP3A4 | |
| SCHEMBL9557493 | 0.79 | CTSD (0.44) | ALDH1A1RAB9AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |