Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557956 | 0.86 | MEN1 (0.49) | CES2CES1RECQLPOLBMEN1 | |
| SCHEMBL9557601 | 0.84 | RECQL (0.39) | CES2CES1RECQLPOLBRIPK1 | |
| SCHEMBL9557428 | 0.83 | RECQL (0.50) | RECQLPOLBMEN1KMT2ACYP3A4 | |
| SCHEMBL9557850 | 0.82 | OPRM1 (0.49) | CES2CES1RECQLPOLBMEN1 | |
| SCHEMBL8174989 | 0.80 | POLB (0.50) | RECQLPOLBKMT2ACYP3A4CYP2C9 | |
| SCHEMBL9557676 | 0.78 | TDP1 (0.48) | CES2CES1RECQLPOLBMEN1 | |
| SCHEMBL9557270 | 0.77 | CES2 (0.49) | CES2CES1RIPK1OPRM1OPRL1 | |
| SCHEMBL9557680 | 0.77 | MEN1 (0.50) | CES2CES1POLBMEN1KMT2A | |
| SCHEMBL9557376 | 0.77 | KMT2A (0.42) | CES2CES1RECQLKMT2ARIPK1 | |
| SCHEMBL9557388 | 0.76 | RAB9A (0.46) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |