Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557376 | 0.94 | KMT2A (0.42) | KMT2ACYP1A2CYP2C19RECQLCES2 | |
| SCHEMBL9557162 | 0.92 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9557428 | 0.88 | RECQL (0.50) | KMT2AMEN1CYP1A2HSD17B10LMNA | |
| SCHEMBL9557966 | 0.86 | CES2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9557283 | 0.86 | CES2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9557173 | 0.85 | CYP1A1 (0.50) | KMT2AMEN1CES2CES1PDK2 | |
| SCHEMBL9557392 | 0.84 | CES2 (0.51) | SMN1; SMN2CYP1A2LMNAL3MBTL1CYP2C19 | |
| SCHEMBL9557624 | 0.84 | CES2 (0.51) | SMN1; SMN2CYP1A2LMNAL3MBTL1CYP2C19 | |
| SCHEMBL9558162 | 0.81 | HPGD (0.48) | SMN1; SMN2TDP1CYP2C19 | |
| SCHEMBL9558095 | 0.81 | ALDH1A1 (0.34) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |