Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557177 | 0.94 | HPGD (0.53) | HPGDTDP1ABCB1PARP1HDAC8 | |
| SCHEMBL9557497 | 0.93 | HPGD (0.49) | HPGDTDP1ABCB1PARP1HDAC8 | |
| SCHEMBL9557401 | 0.91 | KCNK3 (0.47) | HPGDTDP1ABCB1PARP1CYP2C19 | |
| SCHEMBL9557966 | 0.88 | CES2 (0.50) | HPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL9557283 | 0.88 | CES2 (0.50) | HPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL9557162 | 0.88 | ALDH1A1 (0.43) | HPGDTDP1HSD17B1HSD17B2HDAC6 | |
| SCHEMBL9557795 | 0.88 | THRB (0.45) | HPGDABCB1PARP1CYP2C19KCNK3 | |
| SCHEMBL9558223 | 0.82 | ABCB1 (0.48) | ABCB1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL9557357 | 0.82 | HPGD (0.55) | HPGDTDP1HSD17B1HSD17B2ABCB1 | |
| SCHEMBL9557579 | 0.82 | TSHR (0.41) | CYP2C19CYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |