Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557821 | 0.90 | HSP90AA1 (0.38) | HSP90AA1GPR139HPGDROCK2TMEM97 | |
| SCHEMBL9825489 | 0.83 | HSP90AA1 (0.38) | HSP90AA1GPR139HPGDTMEM97SIGMAR1 | |
| SCHEMBL10774850 | 0.82 | TMEM97 (0.43) | HSP90AA1HPGDROCK2TMEM97SIGMAR1 | |
| SCHEMBL9558176 | 0.72 | SLC6A2 (0.43) | HSP90AA1GPR139HPGDKDM4EALDH1A1 | |
| SCHEMBL6566957 | 0.65 | TSHR (0.55) | HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL13450675 | 0.65 | ALOX15 (0.52) | HSP90AA1HPGDKDM4EPIK3CAALDH1A1 | |
| SCHEMBL4146849 | 0.64 | HPGD (0.68) | GPR139HPGDKDM4ENPC1RAB9A | |
| SCHEMBL9558057 | 0.64 | TSHR (0.36) | HSP90AA1HPGDKMT2AALDH1A1GAA | |
| SCHEMBL9557703 | 0.63 | TSHR (0.41) | HSP90AA1GPR139HPGDKDM4EALDH1A1 | |
| SCHEMBL3111273 | 0.63 | KDM4E (0.54) | HSP90AA1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |