Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557821 | 0.83 | HSP90AA1 (0.38) | HSP90AA1HPGDGPR139KDM4ETMEM97 | |
| SCHEMBL9557974 | 0.83 | HSP90AA1 (0.40) | HSP90AA1HPGDGPR139KDM4ETMEM97 | |
| SCHEMBL10774850 | 0.74 | TMEM97 (0.43) | HSP90AA1HPGDTMEM97SIGMAR1LMNA | |
| SCHEMBL10721492 | 0.74 | HPGD (0.41) | HPGDGPR139KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6566957 | 0.69 | TSHR (0.55) | HPGDKDM4E | |
| SCHEMBL29471104 | 0.67 | KMT2A (0.44) | KDM4E | |
| SCHEMBL13450675 | 0.65 | ALOX15 (0.52) | HSP90AA1HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL4146849 | 0.65 | HPGD (0.68) | HPGDGPR139KDM4ELMNA | |
| SCHEMBL9825038 | 0.64 | POLB (0.50) | HPGDLMNA | |
| SCHEMBL3111273 | 0.64 | KDM4E (0.54) | HSP90AA1HPGDKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |