Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767811 | 0.90 | — | — | |
| SCHEMBL30775404 | 0.82 | SORD (0.56) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL4453478 | 0.82 | SORD (0.56) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL9558132 | 0.81 | SORD (0.55) | SORDGPR119 | |
| SCHEMBL9557394 | 0.80 | SORD (0.55) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL29611181 | 0.80 | SORD (0.54) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL209842 | 0.80 | SORD (0.54) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL209844 | 0.80 | SORD (0.54) | SORDAKT1GPR119ROCK1DRD4 | |
| SCHEMBL5758520 | 0.79 | SORD (0.54) | SORDAKT1GPR119ROCK1PARP1 | |
| SCHEMBL2224541 | 0.78 | SORD (0.53) | SORDAKT1GPR119ROCK1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215967-A | AMINOACID DERIVATIVES INHIBITING RENIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-06-01 | — | — | US | disclosed |