SCHEMBL955824

SCHEMBL955824

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nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079683 0.86 TSHR (0.32)
SCHEMBL3727014 0.79 MEN1 (0.48) MEN1KMT2APOLBGAACYP2C9
SCHEMBL21981138 0.78 MEN1 (0.35) MEN1KMT2APOLBGAACYP2C9
SCHEMBL2322350 0.78 TSHR (0.43) MEN1KMT2AGAA
SCHEMBL22733778 0.72 LPAR3 (0.48) MEN1KMT2APOLB
SCHEMBL5961193 0.67 CYP3A4 (0.48) MEN1KMT2APOLBGAACYP2C9
SCHEMBL16660508 0.67 CYP3A4 (0.39) MEN1KMT2APOLB
SCHEMBL16482959 0.66 KMT2A (0.39) MEN1KMT2APOLBGAACYP2C9
SCHEMBL4564740 0.64
SCHEMBL21409643 0.64 LPAR3 (0.48) MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150038588-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2015-02-05 US claimed
US-20090176802-A1 ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS PAPADOPOULOS VASSILIOS 2009-07-09 US claimed
WO-2007092458-A1 ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS SAMARITAN PHARMACEUTICALS, INC. (US) 2007-08-16 WO claimed
US-12559784-B2 In chemico test for toxicity LEBRUN LABS LLC (US) 2026-02-24 US disclosed
US-20250369032-A1 IN CHEMICO TEST FOR TOXICITY LEBRUN LABS LLC (US) 2025-12-04 US disclosed
US-20250101489-A1 IN CHEMICO TEST FOR TOXICITY LEBRUN LABS LLC 2025-03-27 US disclosed
WO-2019180653-A1 COMPOSITIONS, MATERIALS, AND METHODS FOR DEACTIVATING TOXIC AGENTS INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (INSTEM) (IN) 2019-09-26 WO disclosed
US-9024106-B2 Degradation of phosphate esters by high oxidation state molybdenum complexes LEWIS & CLARK COLLEGE (US) 2015-05-05 US disclosed
US-20150038588-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2015-02-05 US disclosed
US-20140357928-A1 DEGRADATION OF PHOSPHATE ESTERS BY HIGH OXIDATION STATE MOLYBDENUM COMPLEXES LEWIS & CLARK COLLEGE (US) 2014-12-04 US disclosed
EP-2563121-A1 METHODS AND COMPOSITIONS FOR PROTECTING AGAINST NEUROTOXIC AGENTS Revalesio Corporation (US) 2013-03-06 EP disclosed
US-20120121656-A1 METHODS AND COMPOSITIONS FOR PROTECTING AGAINST NEUROTOXICITY OF A NEUROTOXIC AGENT, AND IMPROVING MOTOR COORDINATION ASSOCIATED WITH A NEURODEGENERATIVE CONDITION OR DISEASE REVALESIO CORPORATION (US) 2012-05-17 US disclosed
WO-2011137317-A1 METHODS AND COMPOSITIONS FOR PROTECTING AGAINST NEUROTOXIC AGENTS REVALESIO CORPORATION (US) 2011-11-03 WO disclosed
US-7868220-B2 Degradation of phosphate esters by molybdocene and tungstocene derivatives LEWIS & CLARK COLLEGE (US) 2011-01-11 US disclosed
US-20100137672-A1 DEGRADATION OF PHOSPHATE ESTERS BY MOLYBDOCENE AND TUNGSTOCENE DERIVATIVES LEWIS & CLARK COLLEGE (US) 2010-06-03 US disclosed
US-20090176802-A1 ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS PAPADOPOULOS VASSILIOS 2009-07-09 US disclosed
US-20080056933-A1 Automated, ultraviolet, radiofrequency, electrostatic sterilization; hepa filters; chemical, biotoxin decontamination; environmental sampling device, sensor, control system, audio output, data transmitter, global positioning satellite receiver, radio identification tag, vacuum, floor washer, waterproof SOVEREIGN DEED, LLC 2008-03-06 US disclosed
WO-2007092458-A1 ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS SAMARITAN PHARMACEUTICALS, INC. (US) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176802-A1 ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS INA, ACHE, NLN MEN1 2598/4885KMT2A 4026/4885POLB 2564/4885
US-20150038588-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS CHRNA3, GAP43, CHRNA5 MEN1 3486/4885KMT2A 841/4885POLB 3268/4885
US-12559784-B2 In chemico test for toxicity ALPP, ALPI, CUTA MEN1 2759/4885KMT2A 3500/4885POLB 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.