SCHEMBL9558336

SCHEMBL9558336

CC(C)(COCc1ccc(F)c(Oc2ccccc2F)c1)c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
KCNH2 Q12809 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CARM1 Q86X55 3/20 0.37
PRMT6 Q96LA8 3/20 0.37
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
PKM P14618 1/20 0.35
TACR1 P25103 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9029398 0.89 TTR (0.39) SLC6A2SLC6A4KCNH2SLC6A3GRIN2D
SCHEMBL10853926 0.87 FFAR4 (0.39) SLC6A2SLC6A4KCNH2SLC6A3HTT
SCHEMBL10838281 0.87 CARM1 (0.35) SLC6A2SLC6A4KCNH2SLC6A3CARM1
SCHEMBL9558421 0.87 HTR2A (0.41) SLC6A2SLC6A4KCNH2SLC6A3GRIN2D
SCHEMBL9558237 0.85 SLC6A4 (0.40) SLC6A2SLC6A4KCNH2SLC6A3L3MBTL1
SCHEMBL9557909 0.83 MEN1 (0.40) SLC6A4KCNH2GRIN2DGRIN3BGRIN1
SCHEMBL10837314 0.83 HTR2A (0.38) SLC6A4SMN1; SMN2L3MBTL1MEN1KMT2A
SCHEMBL10836788 0.83 L3MBTL1 (0.43) SLC6A4KCNH2GRIN2DGRIN3BGRIN1
SCHEMBL9838544 0.82 SLC6A4 (0.37) SLC6A4KCNH2GRIN2DGRIN3BGRIN1
SCHEMBL10549060 0.82 SLC6A2 (0.38) SLC6A2SLC6A4KCNH2SLC6A3CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed