SCHEMBL10836788

SCHEMBL10836788

Cc1cccc(Oc2cc(COCC(C)(C)c3ccc(Cl)cc3)ccc2F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HTR2A P28223 3/20 0.34
SLC6A4 P31645 3/20 0.34
KCNH2 Q12809 3/20 0.34
FFAR1 O14842 1/20 0.34
MAPT P10636 2/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558237 0.91 SLC6A4 (0.40) L3MBTL1HTR2ASLC6A4KCNH2P2RX4
SCHEMBL9029398 0.89 TTR (0.39) L3MBTL1HTTLMNASMN1; SMN2ALDH1A1
SCHEMBL10849595 0.86 HTT (0.42) L3MBTL1MEN1HTTKMT2ALMNA
SCHEMBL10836883 0.84 TACR1 (0.38) ALDH1A1GAAHTR2ASLC6A4KCNH2
SCHEMBL10853926 0.84 FFAR4 (0.39) MEN1HTTKMT2ALMNASMN1; SMN2
SCHEMBL10836856 0.84 TACR1 (0.36) HTR2ASLC6A4KCNH2FFAR1
SCHEMBL9558421 0.84 HTR2A (0.41) HTR2CHTR2BHTR2ASLC6A4KCNH2
SCHEMBL10549279 0.84 L3MBTL1 (0.42) L3MBTL1MEN1HTTKMT2ALMNA
SCHEMBL9557909 0.83 MEN1 (0.40) L3MBTL1MEN1HTTKMT2ALMNA
SCHEMBL9558336 0.83 SLC6A2 (0.38) L3MBTL1MEN1HTTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed