SCHEMBL9558603

SCHEMBL9558603

Cc1cccc(C(COCc2cccc(Oc3ccccc3)c2)C(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 13/20 0.43
FFAR1 O14842 4/20 0.41
PTGS1 P23219 1/20 0.40
PTGES O14684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558733 0.89 FFAR1 (0.45) TACR1FFAR1PTGS1PTGES
SCHEMBL9558361 0.83 KDM4E (0.51) TACR1FFAR1
SCHEMBL9558288 0.83 PPARG (0.46) TACR1FFAR1PTGES
SCHEMBL9558366 0.82 ALDH1A1 (0.44) TACR1FFAR1
SCHEMBL9558968 0.81 FFAR1 (0.52) FFAR1
SCHEMBL9570571 0.81 CETP (0.43) TACR1FFAR1
SCHEMBL9558340 0.79 PTGES (0.47) TACR1FFAR1PTGS1PTGES
SCHEMBL12444922 0.75 TACR1 (0.54) TACR1
SCHEMBL12444921 0.75 TACR1 (0.54) TACR1
SCHEMBL9559031 0.74 MRGPRX4 (0.39) TACR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed