Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558428 | 0.91 | BRS3 (0.32) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7220511 | 0.78 | AGTR1 (0.35) | — | |
| SCHEMBL8293716 | 0.71 | RAB9A (0.41) | DHODHKDM4E | |
| SCHEMBL6534713 | 0.70 | BRS3 (0.39) | — | |
| SCHEMBL5485083 | 0.68 | NPC1 (0.44) | KDM4E | |
| SCHEMBL10589833 | 0.68 | AGTR1 (0.37) | — | |
| SCHEMBL6007153 | 0.66 | ALOX5AP (0.41) | — | |
| SCHEMBL9155822 | 0.65 | ABL1 (0.47) | — | |
| SCHEMBL29034386 | 0.65 | DCUN1D1 (0.45) | — | |
| SCHEMBL3397570 | 0.65 | DCUN1D1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533840-A1 | TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS. | DU PONT (US) | 1993-03-31 | — | — | EP | claimed |