Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321136 | 0.73 | MAPT (0.50) | HDAC6CRBN | |
| Hydrochloric Acid SCHEMBL11334584 | 0.72 | MAPT (0.49) | ITGB3ITGA2BHDAC6CRBNITGA2 | |
| SCHEMBL7343586 | 0.72 | TDP2 (0.34) | CRBN | |
| SCHEMBL27362455 | 0.72 | TDP2 (0.34) | CRBN | |
| SCHEMBL7699711 | 0.72 | ALDH1A1 (0.51) | — | |
| SCHEMBL11334467 | 0.71 | KDM4E (0.62) | — | |
| SCHEMBL31117282 | 0.71 | CRBN (0.47) | HDAC6CRBN | |
| SCHEMBL10353455 | 0.71 | HDAC3 (0.49) | ITGB3ITGA2BHDAC6 | |
| SCHEMBL10835859 | 0.70 | IP6K1 (0.46) | — | |
| SCHEMBL7338777 | 0.70 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515668-A4 | OXO-TETRAHYDROPYRIDAZINYL-PYRAZOLO 4,3-B)-1,4-BENZOXAZINES | — | 1993-03-10 | — | — | EP | disclosed |