Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23129807 | 0.77 | L3MBTL1 (0.57) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL21891791 | 0.77 | L3MBTL1 (0.57) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL5658218 | 0.75 | CYP1A2 (0.59) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL28665914 | 0.75 | CTRB1 (0.56) | ALDH1A1MAPK1 | |
| SCHEMBL28665913 | 0.75 | CTRB1 (0.56) | ALDH1A1MAPK1 | |
| SCHEMBL20901379 | 0.75 | CYP1A2 (0.61) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL5113566 | 0.75 | CYP1A2 (0.73) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL22193661 | 0.73 | CTRB1 (0.53) | ALDH1A1ALOX15 | |
| SCHEMBL9597177 | 0.73 | PLA2G2C (0.41) | CYP1A2 | |
| SCHEMBL21891842 | 0.73 | CYP1A2 (0.44) | CYP1A2MEN1KMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549727-A1 | CARBOXYLIC ACID ESTERS OF RAPAMYCIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5130307-A | Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| WO-1992005179-A1 | CARBOXYLIC ACID ESTERS OF RAPAMYCIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |