Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844324 | 0.89 | HPGD (0.45) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL8322358 | 0.80 | ALDH1A1 (0.46) | HPGDALDH1A1KDM4ECRHBPCRHR2 | |
| SCHEMBL4699590 | 0.80 | HPGD (0.51) | KMT2AHPGDLMNASMPD1HDAC1 | |
| SCHEMBL4703419 | 0.79 | SMPD1 (0.48) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL30497608 | 0.79 | SMPD1 (0.48) | HPGDKDM4ELMNASMPD1HDAC1 | |
| SCHEMBL595556 | 0.79 | SMPD1 (0.48) | HPGDKDM4ELMNASMPD1HDAC1 | |
| SCHEMBL7845570 | 0.79 | GAA (0.48) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL7846608 | 0.78 | L3MBTL1 (0.46) | HPGDALDH1A1KDM4ELMNASMPD1 | |
| SCHEMBL7846688 | 0.77 | HTR1A (0.49) | HPGDKDM4ELMNASMPD1HDAC1 | |
| SCHEMBL7843936 | 0.76 | MRGPRX4 (0.45) | HPGDALDH1A1KDM4ECRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5255255-A | — | — | None | — | — | JP | disclosed |
| JP-H05255255-A | 6-N-SUBSTITUTED AMINOPICOLINIC ACID DERIVATIVE AND ITS PRODUCTION | KUMIAI CHEM IND CO LTD | 1993-10-05 | — | — | JP | disclosed |