SCHEMBL9559693

SCHEMBL9559693

C[Si](C)(C)C[Si](CI)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9559599 0.82 LMNA (0.33) LMNACYP2A6
SCHEMBL9559741 0.79 NPC1 (0.38) LMNA
SCHEMBL4734052 0.74 LMNA (0.38) LMNACYP2A6
SCHEMBL9559681 0.70 MAPT (0.40)
SCHEMBL9559535 0.69 HTT (0.44)
SCHEMBL196503 0.65 LMNA (0.50) LMNACYP2A6
SCHEMBL9559554 0.65 NPC1 (0.38)
SCHEMBL6477550 0.63 LMNA (0.47) LMNACYP2A6
SCHEMBL7913246 0.63 LMNA (0.47) LMNACYP2A6
SCHEMBL20455818 0.63 LMNA (0.47) LMNACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5235061-A 2,4-disilaalkanes; agriculture KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1993-08-10 US disclosed