Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560497 | 0.93 | ALDH1A1 (0.41) | LTA4HCETPFFAR1FFAR4MRGPRX4 | |
| SCHEMBL9560466 | 0.89 | ALDH1A1 (0.48) | LTA4HCETPFFAR1FFAR4TP53 | |
| SCHEMBL9561343 | 0.89 | CETP (0.41) | CETPFFAR1FFAR4MAPK1 | |
| SCHEMBL9561335 | 0.89 | CETP (0.41) | CETPFFAR1FFAR4MAPK1 | |
| SCHEMBL9560435 | 0.88 | FFAR1 (0.45) | CETPFFAR1FFAR4MAPK14LMNA | |
| SCHEMBL9561097 | 0.88 | MAPK14 (0.44) | LTA4HCETPFFAR1FFAR4MRGPRX4 | |
| SCHEMBL9560382 | 0.87 | FFAR1 (0.41) | CETPFFAR1FFAR4MRGPRX4L3MBTL1 | |
| SCHEMBL9560443 | 0.87 | LTA4H (0.48) | LTA4HCETPFFAR1FFAR4MRGPRX4 | |
| SCHEMBL9560889 | 0.87 | MAPK14 (0.49) | LTA4HCETPFFAR1FFAR4MRGPRX4 | |
| SCHEMBL9560674 | 0.86 | CETP (0.39) | CETPFFAR1FFAR4SMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |