Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 6/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560435 | 0.91 | FFAR1 (0.45) | MAPK14CETPFFAR1FFAR4 | |
| SCHEMBL9560466 | 0.90 | ALDH1A1 (0.48) | MAPK14CETPLTA4HFFAR1FFAR4 | |
| SCHEMBL9560889 | 0.90 | MAPK14 (0.49) | MAPK14CETPMRGPRX4LTA4HEPHX2 | |
| SCHEMBL9560674 | 0.89 | CETP (0.39) | MAPK14CETPFFAR1FFAR4 | |
| SCHEMBL9560412 | 0.88 | LTA4H (0.46) | MAPK14CETPMRGPRX4LTA4HFFAR1 | |
| SCHEMBL9560662 | 0.85 | CETP (0.43) | MAPK14CETPMRGPRX4MEN1KMT2A | |
| SCHEMBL9560585 | 0.84 | MAPK14 (0.39) | MAPK14MRGPRX4MEN1KMT2ALTA4H | |
| SCHEMBL9558335 | 0.84 | TACR1 (0.48) | MAPK14CETPMRGPRX4MEN1KMT2A | |
| SCHEMBL9561335 | 0.82 | CETP (0.41) | CETPFFAR1FFAR4 | |
| SCHEMBL9561343 | 0.82 | CETP (0.41) | CETPFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |