SCHEMBL9560536

SCHEMBL9560536

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccsc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22733813 1.00 LMNA (0.33) LMNA
SCHEMBL9447249 1.00 LMNA (0.33) LMNA
SCHEMBL3294886 1.00 LMNA (0.33) LMNA
SCHEMBL4819895 0.98
SCHEMBL9447467 0.91 L3MBTL1 (0.30)
SCHEMBL673282 0.76 LMNA (0.43) LMNA
SCHEMBL827480 0.74
SCHEMBL30295392 0.72 ESR1 (0.42)
SCHEMBL10825969 0.71 LMNA (0.43) LMNA
SCHEMBL10453463 0.70 TSHR (0.48) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3103428-A None JP disclosed
US-5268448-A Thiophene ring itself not fluorinated SOLVAY S.A. (BE) 1993-12-07 US disclosed
JP-H03103428-A FLUORINATED THIOPHENE, ELECTRICALLY CONDUCTING POLYMER DERIVED FROM THE THIOPHENE, PREPARATION THEREOF, AND APPARATUS CONTAINING THE POLYMER SOLVAY & CIE 1991-04-30 JP disclosed