⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27883763 | 0.87 | CES2 (0.35) | — | |
| Formic Acid SCHEMBL28797184 | 0.85 | PTGS2 (0.31) | — | |
| Aniline SCHEMBL28152989 | 0.83 | TSHR (0.44) | — | |
| SCHEMBL30295392 | 0.81 | ESR1 (0.42) | — | |
| SCHEMBL24277959 | 0.80 | KIF11 (0.38) | — | |
| SCHEMBL9447467 | 0.77 | L3MBTL1 (0.30) | — | |
| SCHEMBL12759665 | 0.77 | NR1H2 (0.43) | — | |
| SCHEMBL15061170 | 0.76 | PDE2A (0.32) | — | |
| SCHEMBL1492956 | 0.76 | — | — | |
| SCHEMBL4819895 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751412-A | Synthesis method of 4-trifluoromethyl thiophene compound | 河南大学 | 2025-04-04 | — | — | CN | claimed |
| US-20200388881-A1 | SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES | ENEVATE CORPORATION | 2020-12-10 | — | — | US | claimed |
| US-20190218216-A1 | PYRIDOPYRIMIDINES DERIVATIVES COMPOUNDS | BIOLAB SANUS FARMACEUTICA LTDA (BR) | 2019-07-18 | — | — | US | claimed |
| US-10280162-B2 | Pyridopyrimidines derivatives compounds | BIOLAB SANUS FARMACEUTICA LTDA (BR) | 2019-05-07 | — | — | US | claimed |
| CN-109627205-A | The preparation method and applications of a kind of carbazyl Isopropanolamine derivatives | 贵州大学 | 2019-04-16 | — | — | CN | claimed |
| US-20180111926-A2 | NEW PYRIDOPYRIMIDINES DERIVATIVES COMPOUNDS | BIOLAB SANUS FARMACEUTICA LTDA (BR) | 2018-04-26 | — | — | US | claimed |
| CN-107074847-A | Novel pyridopyrimidine derivative compound | 生物实验萨纽斯药物有限公司 | 2017-08-18 | — | — | CN | claimed |
| EP-3191099-A2 | DERIVATIVES OF PYRIDOPYRIMIDINES | Biolab Sanus Farmacéutica Ltda (BR) | 2017-07-19 | — | — | EP | claimed |
| US-20160075702-A1 | NEW PYRIDOPYRIMIDINES DERIVATIVES COMPOUNDS | BIOLAB SANUS FARMACEUTICA LTDA (BR) | 2016-03-17 | — | — | US | claimed |
| CN-119751412-A | Synthesis method of 4-trifluoromethyl thiophene compound | 河南大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119751412-A | Synthesis method of 4-trifluoromethyl thiophene compound | 河南大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119751412-A | Synthesis method of 4-trifluoromethyl thiophene compound | 河南大学 | 2025-04-04 | — | — | CN | disclosed |
| US-12227495-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-18 | — | — | US | disclosed |
| CN-112996780-B | Herbicidal compounds | 先正达农作物保护股份公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-101296892-A | PPAR active compounds | PLEXXIKON INC (US) | 2008-10-29 | — | — | CN | disclosed |
| CN-101076519-A | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD (JP) | 2007-11-21 | — | — | CN | disclosed |
| CN-1723197-A | Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH CORP (US) | 2006-01-18 | — | — | CN | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-5145868-A | 7-((Hydroxy(3-hydroxy-4-acylphenyl)alkylene)thio-),4-oxo-4H -chromene; antiallergens; leukotrienes antagonist | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |