Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414312 | 0.81 | PSEN1 (0.41) | SLC6A4SLC6A3SCN5AACHE | |
| SCHEMBL10431044 | 0.77 | ACHE (0.50) | SLC6A4SLC6A3SCN5AACHELMNA | |
| SCHEMBL7413899 | 0.77 | MME (0.41) | SLC6A3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5080329 | 0.77 | HTR1A (0.46) | SLC6A4SCN5AACHESLC6A2CYP1A2 | |
| SCHEMBL18723710 | 0.76 | LTA4H (0.52) | LTA4HALDH1A1LMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL10644448 | 0.72 | HRH3 (0.48) | SMN1; SMN2 | |
| SCHEMBL4212610 | 0.69 | MEN1 (0.44) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6393260 | 0.68 | LTA4H (0.84) | LTA4HSLC6A3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11487151 | 0.68 | ACHE (0.54) | SCN5AACHE | |
| SCHEMBL11494698 | 0.68 | ACHE (0.54) | SCN5AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | disclosed |